Prolapse Conditions and Treatment Methods

Sponsored by Boston Scientific

Lead Researcher: Zhuo Yang

The aims of this research are to develop a 3D finite element model of pelvic organ prolapse, clarify its mechanism of different types of prolapse (Cystocele, Rectocele, and Uterine prolapse), and evaluate its implant treatment method. Currently, our team focuses on developing an approximate 3D computer model of the intact pelvic cavity, which involves the prolapsed organs and the surrounding connective tissues. Biomechanical properties of the tissues were either directly collected from existing literature or calculated by both geometrical and physical experimental data. The abdominal loading condition such as intra-abdominal pressure was introduced into our finite element model to mimic the external environmental condition of different prolapse levels.

In addition, our team is attempting to simplify the complex pelvic supporting system to several segments of simpler mechanical models. The challenge of this work is how to maintain the authenticity while using mechanical notation to represent the pelvic tissues.